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Reversibility

A reversibility test is made to distinguish asthma from other causes of obstructive lung disease.

Following protocol is done:

  1. spirometry test (with at least 2 reproducible flow volume loops)
  2. intake of a bronchodilator through inhalation
  3. 15 minutes pause
  4. a second spirometry test (with at least 2 reproducible flow volume loops)

Now we have 2 sets of flow-volume loops: pre-medication and post-medication.

reversibiliteit
timevolume reversible
FEV1 rises at least 15% after intake of a bronchodilator in case of asthma

In case of asthma, a significant improvement in FEV1 will be seen after the intake of the bronchodilator. A rise in FEV1 of at least 15% is diagnostic for asthma.

Is FEV1 has risen less than 15% after the intake of the bronchodilator, the obstruction is probably caused by another pathology (like COPD) and other tests will be necessary to make a definite diagnosis.